Lipids and Lipid Derivatives
Medchemexpress LLC Octanoic acid, 2-(2-propyn-1-yl)- | 96017-59-3 | MFCD00946863 | 98.0% | 182.26 g/mol | C11H18O2 | 10 MG
2-Hexyl-4-pentynoic acid is an alkynyl-substituted octanoic acid used in biochemical and cell-based research as a histone deacetylase (HDAC) inhibitor. The compound contains a terminal alkyne for click-chemistry applications and is supplied as a colorless to light yellow liquid at high reported purity.
- Alkynyl-substituted octanoic acid with HDAC inhibitory activity.
- Terminal alkyne functional group suitable for copper-catalyzed azide-alkyne cycloaddition (click chemistry).
- High reported purity (98.0%) and supplied as a liquid.
- Small packaging options available, including 10 mg quantities for research use.
- CAS number 96017-59-3; molecular weight 182.26 g/mol.
Cayman Chemical 2-hexyl-4-Pentynoic Acid, Purity: ≥95%, CAS: 96017-59-3, 5 g
Inhibits HDAC activity much more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM); induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM; induces the expression of Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity
Medchemexpress LLC (E)-crotonic acid | 107-93-7 | MFCD00002701 | 50g
NSC 8751 (trans-2-Butenoic acid trans-Crotonic acid) is an unsaturated carboxylic acid compound containing -unsaturated carboxylic acid groups NSC 8751 is one of the important analogs for evaluating the safety of fragrance ingredients and is used to evaluate the toxicological properties of compounds with similar structures When NSC 8751 is applied to local lymph nodes a 50% concentration does not cause skin sensitization Structural analogs of NSC 8751 have been shown to be non-genotoxic trans-Crotonic acid can be used in the preparation of cosmetics and food additives[1][2]
Medchemexpress LLC (E)-3-pentenoic acid | 1617-32-9 | MFCD00063291 | ≥95.0% | 100.12 g·mol-1 | C5H8O2 | 1 G
(E)-3-pentenoic acid is an unsaturated short-chain carboxylic acid supplied as a research reagent and synthetic intermediate for organic chemistry and biochemical studies. It is provided as a high-purity material intended for laboratory research and not for human use.
- Unsaturated carboxylic acid with formula C5H8O2.
- Molecular weight 100.12 g·mol-1.
- Purity ≥95.0%.
- Available in small pack sizes suitable for research, for example 1 g.
- Commonly used as a building block and intermediate in organic synthesis.
- Intended for research use only; not for human or therapeutic applications.
Cayman Chemical 2-hexyl-4-Pentynoic Acid, Purity: ≥95%, CAS: 96017-59-3, 1 g
Inhibits HDAC activity much more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM); induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM; induces the expression of Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity
Apexbio Technology LLC 4-PENTENOIC-ACID-500MG
4-Pentenoic acid (CAS No 591-80-0) is a compound studied in the field of biomedical research particularly for its role in metabolic and enzymatic pathways Originating from synthetic organic chemistry it acts by inhibiting specific enzymes involved in lipid metabolism Its mechanism of action targets pathways associated with fatty acid synthesis and degradation In vitro studies show activity in the nanomolar to low micromolar range making it effective in various laboratory settings Common applications include use in cell models to investigate metabolic diseases and in animal studies for evaluating lipid-regulating therapies It is also utilized in drug screening to identify potential therapeutic compounds Experimental concentrations typically depend on the specific research design
Selleck Chemical LLC Daminozide S4800-500mg
Daminozide (Aminozide DMASA DIMG B 995 Alar Kylar B-NINE SADH) a plant growth regulator selectively inhibits the KDM2/7 JmjC subfamily with IC50 of 1 5 0 7 M for KDM2A It is at least 100-fold selective as an inhibitor of the KDM2/7 subfamily over the other demethylase subfamily members tested with IC50s of 2 M or less against KDM2A PHF8 and KIAA1718 and IC50s of 127 M for KDM3A or greater (mM range) against other demethylases
Selleck Chemical LLC Eicosapentaenoic Acid
Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid with antiinflammatory properties and is present in fish and fish oils including salmon cod and krill oils